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Related Experiment Videos

Maintenance ECT in intractable manic-depressive disorders

J M Vanelle1, H Loo, A Galinowski

  • 1Service Hospitalo Universitaire de Santé Mentale et de Thérapeutique, Paris V René Descartes University, France.

Convulsive Therapy
|September 1, 1994
PubMed
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Maintenance electroconvulsive therapy (ECT-M) significantly reduces hospitalizations for patients with recurrent mood disorders. This long-term treatment shows high remission rates, especially for rapid-cycling and delusional depression.

Area of Science:

  • Psychiatry
  • Neurology

Background:

  • Recurrent unipolar or bipolar mood disorders pose significant challenges in long-term management.
  • Intractable mood disorders often exhibit poor response to pharmacotherapy.

Purpose of the Study:

  • To evaluate the efficacy and long-term outcomes of maintenance electroconvulsive therapy (ECT-M) for patients with intractable recurrent mood disorders.

Main Methods:

  • A cohort of 22 patients with treatment-resistant mood disorders underwent maintenance ECT (ECT-M) for over 18 months.
  • Treatment involved approximately monthly ECT sessions.
  • Patient outcomes were assessed based on hospitalization rates, relapse frequency, and remission status (DSM-III-R criteria).

Main Results:

  • Hospitalization decreased from 44% of the year to 7% (p < 0.001).

Related Experiment Videos

  • Relapses requiring admission occurred once every 16 months.
  • Full remission was achieved in 45% of patients, and partial remission in 27%.

    • Conclusions:

    • Maintenance ECT (ECT-M) is a highly effective long-term treatment for intractable recurrent mood disorders, significantly reducing hospitalizations.
    • ECT-M demonstrates particularly encouraging results for rapid-cycling and drug-refractory delusional depressed patients, with high remission rates.