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Use of flutamide for self-induced androgen excess. A case report
R S Howe1, R P Chow, C L Stevens
1Department of Obstetrics and Gynecology, Baystate Medical Center, Springfield, Massachusetts.
The Journal of Reproductive Medicine
|October 1, 1994
Abstract:
A 28-year-old woman developed hirsutism, facial edema and clitoromegaly after self-injection of long-acting synthetic androgens. The symptoms were ameliorated by administration of flutamide with a combination oral contraceptive. Flutamide appears to be useful in preventing sequelae of acute androgen excess in women and may be a rational therapy for chronic treatment of androgen excess in women.