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[Congenital urethra valves; experiences in 73 children]
J de Jongh-van Hoof1, J D de Vries, L A Monnens
1Afd. Kindergeneeskunde, Academisch Ziekenhuis, Nijmegen.
Objective:
To inventory symptoms of children with urethral valves, and their prognosis.
Design:
Descriptive.
Setting:
Department of paediatrics and urology, University of Nijmegen.
Methods:
Symptoms were evaluated from clinical data and interviews of the parents of 73 patients. The glomerular filtration rate (GFR) was calculated from the serum creatinine level by the method of Counahan.
Results:
Symptoms indicating an urethral obstruction, e.g. diminished urinary jet, were rare (20% of the children). General symptoms prevailed: vomiting, anorexia, growth failure, fever. After 2 years 11 out of 53 children had a GFR < 25 ml/min/1.73 m2 body surface area.
Conclusion:
Specific symptoms indicating an urethral obstruction are rare. The glomerular filtration is often diminished. There are no measures to prevent loss of renal function.