Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Autologous bone marrow transplantation]

T Klingebiel¹, R Handgretinger, D Niethammer

¹Universitätskinderklinik, Abteilung I, Tübingen.

Infusionstherapie Und Transfusionsmedizin

|November 1, 1994

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Stem cell transplantation.

Klinische Padiatrie·2013

Same author

Radiolabeled metaiodobenzylguanidine (mibg) in diagnosis and therapy of neuroblastoma - results from basic research (review).

International journal of oncology·2011

Same author

Identification and selective depletion of alloreactive T-cells for adoptive immunotherapy.

Laboratory hematology : official publication of the International Society for Laboratory Hematology·2010

Same author

Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000.

Leukemia·2009

Same author

Efficient in vitro generation of adult multipotent cells from mobilized peripheral blood CD133+ cells.

Cell proliferation·2008

Same author

Cellular immune reconstitution after haploidentical transplantation in children.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation·2008

Same journal

Determination and Successful Transfusion of Anti-Gerbich-Positive Red Blood Cells in a Patient with a Strongly Reactive Anti-Gerbich Antibody.

Infusionstherapie und Transfusionsmedizin·2000

Same journal

Coexisting Anti-I/i Plus Anti Pr Cold Agglutinins in Individual Sera.

Infusionstherapie und Transfusionsmedizin·2000

Same journal

Comparison of Solvent/Detergent-Inactivated Plasma and Fresh Frozen Plasma under Routine Clinical Conditions.

Infusionstherapie und Transfusionsmedizin·2000

Same journal

Transfusion-Associated Infections with Cytomegalovirus and Other Human Herpesviruses.

Infusionstherapie und Transfusionsmedizin·2000

Same journal

Arificial Oxygen Carriers as Red Blood Cell Substitutes - Perfluorocarbons and Cell-Free Hemoglobin.

Infusionstherapie und Transfusionsmedizin·2000

Same journal

Platelet Concentrates from Automated Apheresis - Past, Present and Future Developments.

Infusionstherapie und Transfusionsmedizin·2000

See all related articles

Autologous bone marrow transplantation (ABMT) offers a dose-escalation strategy for treating various cancers in children and adults. This review covers the principles, indications, challenges, and stem cell sources, including peripheral blood stem cells (PBSC), with a focus on neuroblastoma outcomes.

Area of Science:

Hematology
Oncology
Pharmacology

Context:

Autologous bone marrow transplantation (ABMT) is an established oncological treatment.
The application of ABMT is expanding to a wider range of malignancies in pediatric and adult patients.
Stem cell sources for ABMT include bone marrow and peripheral blood stem cells (PBSC).

Purpose:

To discuss the fundamental principles of ABMT.
To outline the key indications for ABMT in treating malignancies.
To review the challenges and advancements in ABMT, including the use of PBSC.

Summary:

ABMT leverages dose-response principles from pharmacology for cancer treatment.
Bone marrow from the iliac crest is a traditional stem cell source, but PBSC offer expanded therapeutic possibilities.

Related Experiment Videos

The review details the application of ABMT in neuroblastoma, presenting treatment outcomes.

Impact:

Provides a comprehensive overview of ABMT for clinicians and researchers.
Highlights the importance of stem cell source selection in optimizing ABMT efficacy.
Offers insights into the successful application of ABMT in treating challenging pediatric malignancies like neuroblastoma.