Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Transluminal extraction coronary atherectomy

B H Annex1, M H Sketch, R S Stack

  • 1Department of Medicine, Duke University Medical Center, Durham, North Carolina.

Cardiology Clinics
|November 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Inhibiting Anti-angiogenic VEGF165b Activates a Novel miR-17-20a-Calcipressin-3 Pathway that Revascularizes Ischemic Muscle in Peripheral Artery Disease.

Research square·2023
Same author

Acute myocardial infarction.

Postgraduate medicine·2016
Same author

Recombinant PAI-1 therapy restores myoendothelial junctions and erectile function in PAI-1-deficient mice.

Andrologia·2015
Same author

Adeno-associated virus serotype 9 efficiently targets ischemic skeletal muscle following systemic delivery.

Gene therapy·2013
Same author

Exercise dose response in muscle.

International journal of sports medicine·2012
Same author

Intravascular stents.

Trends in cardiovascular medicine·2011
Same journal

The Heart-Brain Connection.

Cardiology clinics·2026
Same journal

Overcoming Psychological Barriers to Treatment Adherence: The Case of Antihypertensive Medication.

Cardiology clinics·2026
Same journal

Cardio-oncology Rehabilitation and Mental Health: Current Evidence and Future Perspectives.

Cardiology clinics·2026
Same journal

Cardiac Rehabilitation and Mental Health.

Cardiology clinics·2026
Same journal

Best-Practice Mental Health Interventions Following Acute Cardiovascular Events.

Cardiology clinics·2026
Same journal

Positive Psychology Interventions and Cardiovascular Health: Frequency and Duration to Sustain Cardiovascular Benefits.

Cardiology clinics·2026
See all related articles

The TEC atherectomy catheter effectively removes atheroma and thrombus, showing favorable success rates in coronary lesions and bypass grafts. Further trials are needed to define its optimal role in interventional cardiology.

Area of Science:

  • Interventional Cardiology
  • Vascular Surgery
  • Medical Device Technology

Background:

  • The TEC (Transluminal Extraction Catheter) is an atherectomy device designed to excise and aspirate atheromatous plaque and thrombus.
  • It received FDA marketing approval in 1993 for treating coronary vasculature lesions.
  • Clinical investigation has spanned over six years prior to its widespread adoption.

Purpose of the Study:

  • To evaluate the clinical and lesion success rates of the TEC atherectomy catheter in a large patient registry.
  • To investigate the mechanisms of action and efficacy of the TEC in various lesion types, including those with intraluminal thrombus.
  • To identify potential niches for the TEC in interventional cardiology, particularly in complex lesions and bypass grafts.

Main Methods:

Related Experiment Videos

  • Analysis of data from the US TEC Multicenter Registry.
  • Utilizing percutaneous angioscopy and intravascular ultrasound to visualize and understand the TEC's interaction with atheroma and thrombus.
  • Assessment of procedural success in native coronary vessels and saphenous vein bypass grafts, including challenging angiographic features.

Main Results:

  • Favorable overall clinical and lesion success rates were observed in the registry.
  • Similar success rates were achieved in both native coronary arteries and saphenous vein bypass grafts.
  • The TEC demonstrated efficacy in treating lesions with unfavorable features like ostial location, intraluminal thrombus, and total occlusions.
  • Angioscopy confirmed thrombus removal, especially in unstable coronary syndromes, but noted frequent intimal disruptions post-procedure.

Conclusions:

  • The TEC atherectomy catheter shows promise for treating complex coronary lesions, including those with intraluminal thrombus and in saphenous vein grafts.
  • While effective, the device can cause intimal disruptions, necessitating further evaluation in randomized trials.
  • Potential applications include managing diffusely diseased bypass grafts and as primary therapy for thrombotic lesions, possibly with adjunctive treatments.