The evolving spectrum of eosinophilia myalgia syndrome

Eosinophilia myalgia syndrome (EMS) is a toxin-induced illness that provides a model for the understanding of idiopathic immune-mediated diseases that have overlapping features. The clinical development and chronic sequelae of EMS, its relationship to related disorders, and the accumulating data suggesting an important role for immune mechanisms in the pathogenesis of this disease are reviewed in this article.