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Diffuse disease of the liver: radiologic-pathologic correlation

P J Mergo1, P R Ros, P C Buetow

  • 1Department of Radiology, University of Florida College of Medicine, Gainesville 32610-0374.

Radiographics : a Review Publication of the Radiological Society of North America, Inc
|November 1, 1994
PubMed
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Cross-sectional imaging, especially magnetic resonance (MR) imaging, aids in diagnosing diffuse liver diseases by clarifying overlapping symptoms and potentially avoiding biopsies. These advanced techniques characterize various liver conditions, correlating imaging findings with pathology.

Area of Science:

  • Radiology
  • Hepatology
  • Medical Imaging

Background:

  • Diffuse liver diseases present overlapping clinical and laboratory findings, complicating diagnosis.
  • Traditional diagnostic methods may necessitate invasive procedures like liver biopsy.

Purpose of the Study:

  • To highlight the increasing role of cross-sectional imaging in diagnosing diffuse liver diseases.
  • To demonstrate how advanced imaging techniques characterize hepatic parenchymal and architectural changes.
  • To correlate imaging findings with underlying pathologic features for improved understanding.

Main Methods:

  • Utilizing cross-sectional imaging, particularly magnetic resonance (MR) imaging.
  • Characterizing metabolic, vascular, toxic, infectious, and neoplastic diffuse liver diseases.

Related Experiment Videos

  • Correlating computed tomographic (CT) and MR imaging findings with pathologic features.

    • Main Results:

    • Advanced imaging clarifies overlapping manifestations, potentially obviating the need for biopsy.
    • MR imaging enables detailed characterization of hepatic changes, linking them to pathology.
    • Imaging techniques can identify common (e.g., cirrhosis, fatty liver) and uncommon (e.g., schistosomiasis, amyloidosis) diffuse liver diseases.

    Conclusions:

    • Cross-sectional imaging is a valuable tool for diagnosing diffuse liver diseases.
    • Advanced MR and CT imaging improve the characterization and understanding of liver pathology.
    • These imaging modalities offer a non-invasive approach to diagnosing a wide spectrum of liver conditions.