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Production and purification of hybrid Ty-VLPs
N R Burns1, J E Gilmour, S M Kingsman
1British Bio-Technology Ltd., Cowley, Oxford, UK.
Molecular Biotechnology
|April 1, 1994
Abstract:
This article describes how pure Ty-VLPs (virus-like particles) can be prepared from hybrid Ty-VLPs. Many different hybrid Ty-VLPs have been produced and may be easily purified. Since the sedimentation properties of different hybrid Ty-VLPs are similar, a simple purification process can be used for any VLP. This fast, versatile, and easy process allows for the production of a variety of recombinant proteins.