Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quantitative sensory testing: methodology, applications, and future directions

G Gruener1, P J Dyck

  • 1Peripheral Neuropathy Research Laboratory, Mayo Clinic, Rochester, MN 55905.

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
|November 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Identification of needs for an assistive robotic arm in individuals with tetraplegia: a mixed-methods approach.

Journal of neuroengineering and rehabilitation·2025
Same author

Early data on long-term efficacy and safety of inotersen in patients with hereditary transthyretin amyloidosis: a 2-year update from the open-label extension of the NEURO-TTR trial.

European journal of neurology·2020
Same author

Does prediabetes cause small fiber sensory polyneuropathy? Does it matter?

Journal of the neurological sciences·2015
Same author

Retrospective study of a TTR FAP cohort to modify NIS+7 for therapeutic trials.

Journal of the neurological sciences·2014
Same author

Autonomic dysfunction in chronic inflammatory demyelinating polyradiculoneuropathy.

Neurology·2012
Same author

The diflunisal trial: update on study drug tolerance and disease progression.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis·2011
Same journal

Surface EEG to Identify Cognitive Motor Dissociation After Acute Brain Injury.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

The Physics and Physiology of Electrical Stimulation of the Brain.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

Neurophysiology in Postanoxic Encephalopathy: Pathophysiology, Prognosis, and Treatment.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

A Review on the Functional Connectivity of the Human Opercular Cortex.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

Surgical Aspects of Opercular Epilepsies.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
Same journal

Cost-Effectiveness of EEG Monitoring in Hypoxic-Ischemic Brain Injury After Cardiac Arrest.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026
See all related articles

Quantitative sensory testing (QST) uses precise psychophysical methods to measure sensory perception in health and disease. This standardized approach quantifies sensory loss, aiding in disease diagnosis and clinical trials.

Area of Science:

  • Neuroscience
  • Psychophysics
  • Clinical Measurement

Background:

  • Quantitative sensory testing (QST) relies on established psychophysical methods to define stimuli and responses.
  • Advancements in computing and electronics enabled precise, quantifiable, and graded stimulus delivery for QST.
  • Specialized software allows for programmed testing algorithms, ensuring accurate and error-free data collection.

Purpose of the Study:

  • To detail the principles and applications of quantitative sensory testing (QST).
  • To highlight QST's role in standardizing clinical examinations and quantifying sensory perception.
  • To discuss QST's utility in identifying and tracking sensory abnormalities in various health conditions.

Main Methods:

  • Utilizes well-developed psychophysical methods with precisely controlled stimuli (type, magnitude, presentation).

Related Experiment Videos

  • Employs computer-controlled systems with transducers and software for accurate stimulus generation and response analysis.
  • Incorporates standardized algorithms for threshold determination and comparison with normative data.

    • Main Results:

    • QST quantifies modality-specific detection and suprathresholds in healthy individuals and patients.
    • Results can be correlated with neurophysiological measures (e.g., nerve action potentials) and fiber characteristics.
    • Identifies patterns of sensory abnormality, suggesting specific diseases and monitoring disease progression.

    Conclusions:

    • QST provides a standardized method for assessing sensory function, crucial for clinical diagnosis.
    • It plays a vital role in detecting, characterizing, and quantifying sensory deficits.
    • QST is valuable in both epidemiologic studies and controlled clinical trials for evaluating sensory disturbances.