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Drug-nutrient interactions in three long-term-care facilities

C W Lewis¹, E A Frongillo, D A Roe

¹Cornell University, Ithaca, NY.

Journal of the American Dietetic Association

|March 1, 1995

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Residents in long-term-care facilities face significant risks of drug-nutrient interactions (DNIs) due to polypharmacy. Proactive monitoring and interventions are crucial to ensure patient safety and optimize therapeutic outcomes.

Area of Science:

Gerontology
Clinical Pharmacy
Nutritional Science

Background:

Long-term-care facilities house elderly and chronically ill patients often requiring multiple medications.
Polypharmacy in this population increases the likelihood of adverse events, including drug-nutrient interactions (DNIs).

Purpose of the Study:

To evaluate the prevalence and types of potential drug-nutrient interactions (DNIs) among residents in three long-term-care facilities.
To identify specific drug-nutrient interactions posing the greatest risk in this setting.

Main Methods:

A retrospective chart audit was conducted across three central New York long-term-care facilities.
Data from 53 randomly selected patients per facility over six months were analyzed using a computerized algorithm to assess DNI risk.

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Mean drug consumption, drug usage patterns, and incidence of potential DNIs were documented.

Main Results:

Patients consumed an average of 4.04 to 5.27 drugs per month, with a mean risk of 1.43 to 2.69 potential DNIs per patient per month.
The most frequent potential DNIs involved gastrointestinal absorption and electrolyte balance.
Significant variation in DNI risk was observed across the facilities.

Conclusions:

Elderly, chronically ill patients in long-term-care facilities are at considerable risk for specific drug-nutrient interactions.
Enhanced pharmacologic and nutritional management, alongside timely patient monitoring, is essential.
Dietitians are vital in educating healthcare professionals and developing policies to mitigate DNIs.