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Intramedullary spinal cord lipomas

M Lee1, A R Rezai, R Abbott

  • 1Department of Neurosurgery, New York University Medical Center, New York.

Journal of Neurosurgery
|March 1, 1995
PubMed
Summary
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Intramedullary spinal cord lipomas are rare tumors. Surgical resection offers pain relief but generally does not improve neurological function in patients with significant compromise.

Area of Science:

  • Neurosurgery
  • Neurology
  • Oncology

Background:

  • Intramedullary spinal cord lipomas are exceptionally rare, comprising a small fraction of spinal cord tumors.
  • Literature primarily consists of isolated case reports, highlighting their rarity.

Purpose of the Study:

  • To report on a series of six patients with intramedullary spinal cord lipomas.
  • To analyze the management and outcomes of these rare spinal cord tumors.

Main Methods:

  • Retrospective review of six patients diagnosed with intramedullary spinal cord lipomas between 1985 and 1993.
  • All patients underwent diagnostic imaging, including MRI, and subtotal tumor resection.
  • Follow-up ranged from 12 to 96 months to assess neurological recovery.

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Main Results:

  • Patients presented with significant neurological deficits, including pain, sensory changes, weakness, and incontinence.
  • Subtotal resection (40-70%) resulted in pain resolution for all patients.
  • No patient achieved full neurological recovery; three had independent function with deficits, and three had severe deficits.

Conclusions:

  • Intramedullary spinal cord lipomas carry a poor prognosis for neurological recovery, especially in patients with pre-existing deficits.
  • Surgical intervention primarily addresses pain and may not restore lost neurological function.