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[The hemodynamic changes during the intraperitoneal hyperthermic perfusion under induced hypothermia]
1Department of Anesthesia, Social Insurance Funabashi Central Hospital, Funabashi.
Masui. the Japanese Journal of Anesthesiology
|November 1, 1994
Summary
Intraperitoneal hyperthermic perfusion (IPHP) with induced hypothermia showed a correlation between oxygen consumption (VO2) and pulmonary artery temperature (PAT). IPHP is not recommended for patients with ischemic heart disease due to potential hemodynamic changes.
Area of Science:
- Physiology
- Oncology
- Critical Care Medicine
Context:
- Intraperitoneal hyperthermic perfusion (IPHP) is a therapeutic procedure.
- Induced hypothermia is used to mitigate adverse effects.
- Monitoring physiological parameters is crucial during IPHP.
Purpose:
- To investigate whole-body oxygen consumption (VO2) and hemodynamic changes during IPHP.
- To assess the impact of induced hypothermia on patient safety.
- To compare physiological responses during IPHP with total body hyperthermia (TBH).
Summary:
- A significant correlation was observed between VO2 and pulmonary artery temperature (PAT) during IPHP.
- VO2 increased with rising PAT, but to a lesser extent than during TBH.
- Heart rate increased proportionally with body temperature, with a faster rise rate during IPHP compared to TBH.
- IPHP may not be suitable for patients with ischemic heart disease due to significant hemodynamic shifts.
Impact:
- Provides insights into the physiological demands of IPHP.
- Informs clinical decisions regarding patient selection for IPHP.
- Highlights the importance of careful monitoring of cardiovascular parameters during hyperthermic therapies.