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Published on: September 13, 2022
[Congenital cholelithiasis]
1Toldy Ferenc Kórház, Csecsemö- és Gyermekosztály, Cegléd.
Insights
This study found that some gallstones in newborns disappear spontaneously. Ursodeoxycholate may help resolve persistent connatal gallstones.
Area of Science:
- Neonatal Medicine
- Pediatric Gastroenterology
- Medical Ultrasound
Background:
- Gallstones are uncommon in newborns, but intrauterine formation is possible.
- Maternal factors may influence the development of congenital gallstones.
Observation:
- Ultrasound screening of 6000 newborns identified two cases of gallstones and echogenic spots in three others.
- One of the two identified gallstones and the echogenic spots resolved within six months.
Findings:
- Congenital gallstones may have a higher spontaneous resolution rate.
- Persistent gallstones in newborns might require medical intervention.
Implications:
- Understanding maternal risk factors is crucial for predicting intrauterine gallstone formation.
- Ursodeoxycholate could be a potential treatment for persistent neonatal gallstones.
Abstract:
The author screened 6000 newborns with ultrasound and two gallstones have found (in age 1 and 2 days). He found numerous floating echogenic spots in the gallbladder of three other newborns. The spots and one of two gallstones disappeared, the other gallstone did not changed during the first 6 months of life. The author thinks, the maternal predisposing factors have importance in the formation of intrauterine gallstones. These factors disappear after delivery and the connatal gallstones often disappear spontaneously. If they don't, the author thinks it worthy to try to resolve them with ursodeoxycholate.
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