[Proliferative diffuse glomerulonephritis (author's transl)]

Some aspects of the diffuse proliferative glomerulonephritis have been examined: initial renal failure, evolution of the lesions, crioglobulinemia. Thirty-five of 88 cases presented high urea levels, in 3 of them with acute renal failure transient hemodialysis treatment was needed, only one case progressed toward chronic renal failure. Anatomic alterations either in the case of exudative or proliferative damages improved but not up to complete healing: mesangial tickening and local proliferation has been observed. Crioglobulinemia was found in 14 of 21 cases. The disappearance in two cases of the crioglobulinemia was accompanied by a significative improvement of the hystology; a persistent crioglobulinemia usually accompanies unmodified histologic alterations.