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Mouthrinses

D Adams1, M Addy

  • 1Department of Basic Dental Science, Dental School, Cardiff, Wales.

Advances in Dental Research
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

This review examines recent mouthrinse research, finding chlorhexidine effective for plaque and gingivitis but with drawbacks. Newer formulations inhibiting bacterial adhesion show promise for oral hygiene adjuncts.

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Area of Science:

  • Oral hygiene
  • Pharmacology
  • Dental research

Background:

  • Mouthrinses have historical medicinal and cosmetic uses.
  • Recent scientific research and clinical trials investigate mouthrinse ingredients.
  • Chlorhexidine mouthrinses marked a significant advancement in chemical disease prevention.

Purpose of the Study:

  • To review literature on mouthrinses over the past five years.
  • To focus on anti-plaque, anti-gingivitis, and anti-calculus formulations.
  • To evaluate clinical trial methodologies and outcomes for mouthrinses.

Main Methods:

  • Literature review of studies published within the last five years.
  • Analysis of clinical trial data for established and newer mouthrinse formulations.

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  • Discussion of methodologies for conducting clinical trials of mouthrinses.

    • Main Results:

    • Chlorhexidine demonstrates superior efficacy in reducing plaque and gingivitis.
    • Chlorhexidine's drawbacks include taste and staining issues.
    • Newer rinses inhibiting bacterial adhesion show potential, with some formulations like Plax having mixed results.

    Conclusions:

    • Standardization of clinical trial methodology for mouthrinses is needed.
    • Chlorhexidine remains highly effective but has limitations.
    • Further research into novel formulations and combinations of active ingredients is recommended for improved oral care.