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Updated: Aug 12, 2026

Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three Dimensional Documentation
Published on: May 23, 2017
A zinc-containing fiber system of thalamic origin
1Laboratory for Neurobiology, University of Texas at Dallas, Richardson 75080.
Abstract:
Zinc-containing neurons are cells that sequester zinc presynaptically and release it when active. Previously such neurons have been found almost exclusively in cerebrocortical and amygdalar regions. Here we describe a thalamo-cortical pathway that is zinc-containing, namely, the projection from the anterodorsal nucleus of the thalamus to the subicular cortex. The pathway was identified by the zinc-specific retrograde transport methods; its addition to the zinc-containing cerebral circuitry reinforces the association of the zinc-containing terminals with cortico-limbic systems.
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