Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Irritable bowel syndrome

D A Drossman1

  • 1Department of Medicine, University of North Carolina at Chapel Hill 27599-7080.

The Gastroenterologist
|December 1, 1994
PubMed
Summary
This summary is machine-generated.

Irritable bowel syndrome (IBS) is a common disorder stemming from gut-brain dysregulation. Recent advances improve understanding and treatment through integrated pharmacological and behavioral approaches.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development, content validity, and cross-cultural adaptation of a patient-reported outcome measure for real-time symptom assessment in irritable bowel syndrome.

Neurogastroenterology and motility·2017
Same author

Communication breakdown between physicians and IBS sufferers: what is the conundrum and how to overcome it?

The journal of the Royal College of Physicians of Edinburgh·2017
Same author

Development and validation of the Patient-Physician Relationship Scale among patients with irritable bowel syndrome.

Neurogastroenterology and motility·2017
Same author

What's new in Rome IV?

Neurogastroenterology and motility·2017
Same author

Centrally targeted pharmacotherapy for chronic abdominal pain.

Neurogastroenterology and motility·2015
Same author

Development and pilot testing of an integrated, web-based self-management program for irritable bowel syndrome (IBS).

Neurogastroenterology and motility·2014
Same journal

Pseudomyxoma peritonei.

The Gastroenterologist·1998
Same journal

Update on obesity treatment.

The Gastroenterologist·1998
Same journal

Pathophysiology and treatment of hepatorenal syndrome.

The Gastroenterologist·1998
Same journal

Common pediatric esophageal disorders.

The Gastroenterologist·1998
Same journal

The technical aspects of biofeedback therapy for defecation disorders.

The Gastroenterologist·1998
Same journal

Magnetic resonance cholangiopancreatography: a new technique for evaluating the biliary tract and pancreatic duct.

The Gastroenterologist·1998
See all related articles

Area of Science:

  • Gastroenterology
  • Neurogastroenterology
  • Psychosomatic Medicine

Background:

  • Irritable bowel syndrome (IBS) presents significant disability and healthcare costs.
  • Past challenges in IBS diagnosis and management stemmed from incomplete pathophysiology understanding, imprecise diagnostics, and lack of specific treatments.
  • Recent advancements in epidemiological, physiological, and psychosocial data have enhanced understanding of IBS.

Purpose of the Study:

  • To review the current understanding of Irritable Bowel Syndrome (IBS) pathophysiology.
  • To outline modern diagnostic criteria and treatment strategies for IBS.
  • To highlight the role of integrated approaches in managing IBS.

Main Methods:

  • Review of recent epidemiological, physiological, and psychosocial data concerning IBS.

Related Experiment Videos

  • Application of multinational symptom-based "Rome" criteria for diagnosis.
  • Analysis of integrated pharmacological and behavioral treatment modalities.

    • Main Results:

    • IBS is understood to arise from dysregulation in intestinal motor, sensory, and central nervous system functions.
    • Symptoms result from disturbed intestinal motility and heightened visceral sensitivity.
    • Psychosocial factors significantly modulate the IBS illness experience and clinical outcomes.

    Conclusions:

    • The "Rome" criteria have improved diagnostic specificity for IBS.
    • Effective IBS management requires an integrated pharmacological and behavioral approach.
    • Treatment strategies are tailored based on illness severity and physiological/psychosocial determinants.