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Spontaneous colitis cystica profunda in captive tamarins
A S Gozalo1, G E Dagle, E J Montoya
1Center for Reproduction and Conservation of Nonhuman Primates, Instituto Veterinario de Investigaciones Tropicales, Universidad Nacional Mayor de San Marcos, Iquitos, Peru.
Journal of Medical Primatology
|July 1, 1994
Summary
Chronic colitis and colitis cystica profunda were diagnosed in 12.5% of tamarins studied. This is the first report of colitis cystica profunda in nonhuman primates, highlighting a significant finding in tamarin health.
Area of Science:
- Veterinary Pathology
- Primate Medicine
- Comparative Pathology
Background:
- Nonhuman primates, particularly tamarins (Saguinus spp.), are vital models in biomedical research.
- Understanding diseases affecting captive primate populations is crucial for conservation and research integrity.
- Chronic gastrointestinal conditions can impact the health and welfare of nonhuman primates.
Purpose of the Study:
- To investigate the prevalence and pathological characteristics of chronic colitis in Saguinus mystax and Saguinus labiatus.
- To identify and report the occurrence of colitis cystica profunda in a nonhuman primate population for the first time.
- To document findings from necropsies conducted between 1987 and 1990.
Main Methods:
- Necropsy examinations of 232 tamarins (133 Saguinus mystax, 99 Saguinus labiatus) that died at a conservation center.
- Gross pathological assessment of the cecal and colonic mucosa.
- Microscopic examination for the diagnosis of colitis cystica profunda.
Main Results:
- Chronic colitis was diagnosed in 23 tamarins (9.9%) with characteristic mucosal changes including greyish discoloration and yellowish cysts.
- Colitis cystica profunda was identified in an additional six cases, bringing the total to 29 cases (12.5%).
- The observed cysts measured 1-4 mm and bulged the colonic mucosa.
Conclusions:
- This study reports the first known cases of colitis cystica profunda in nonhuman primates, specifically in tamarins.
- The findings indicate a significant prevalence of chronic colitis and its deeper form in this captive tamarin population.
- Further research into the etiology and implications of colitis cystica profunda in nonhuman primates is warranted.