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Hemifacial spasm and osteitis deformans

E B Ing1, P J Savino, T M Bosley

  • 1Neuro-ophthalmology Service, Wills Eye Hospital, Philadelphia, PA 19107.

American Journal of Ophthalmology
|March 1, 1995
PubMed
Summary
This summary is machine-generated.

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Paget's disease of bone can cause hemifacial spasm due to temporal bone overgrowth. While bisphosphonates were ineffective, botulinum toxin successfully treated the spasm in this patient.

Area of Science:

  • Neurology
  • Endocrinology
  • Radiology

Background:

  • Osteitis deformans (Paget's disease) is a chronic bone disorder.
  • Hemifacial spasm is an involuntary twitching of facial muscles.

Observation:

  • A patient with Paget's disease and hemifacial spasm presented with significant temporal bone overgrowth.
  • Imaging revealed no vascular compression of the facial nerve root.

Findings:

  • Intravenous pamidronate, a bisphosphonate, did not resolve the hemifacial spasm.
  • Botulinum toxin injection provided 22 weeks of spasm relief.

Implications:

  • Bisphosphonates may not be effective for Paget's disease-associated hemifacial spasm.
  • Botulinum toxin is a viable treatment option for this condition.

Related Experiment Videos

  • Further research is needed to explore bisphosphonate efficacy in pagetoid hemifacial spasm.