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Varicella vaccine for prevention of chickenpox
1Division of Pediatric Infectious Diseases, Rhode Island Hospital.
Insights
Varicella vaccine, proven safe and effective over 12 years, will be released in 1995. Recommendations include one dose for infants and children, and two doses for adolescents and adults.
Area of Science:
- Immunology
- Vaccinology
- Public Health
Background:
- Varicella (chickenpox) is a common childhood illness.
- A safe and effective vaccine has been developed after 12 years of clinical trials.
- Anticipated release of the varicella vaccine is scheduled for early 1995.
Purpose of the Study:
- To outline the proposed recommendations for the use of the new varicella vaccine.
- To detail the recommended vaccination schedules for different age groups.
- To inform healthcare providers about the upcoming availability and usage guidelines.
Main Methods:
- Clinical trials conducted over a 12-year period.
- Evaluation of vaccine safety and efficacy.
- Development of dosing recommendations based on age and susceptibility.
Main Results:
- The varicella vaccine demonstrated safety and effectiveness in extensive clinical trials.
- A single-dose schedule is proposed for routine infant immunization (12-18 months) and catch-up immunization (18 months to 12 years).
- A two-dose schedule is recommended for susceptible adolescents and adults.
Conclusions:
- The varicella vaccine is poised for release, offering a new tool for disease prevention.
- The proposed recommendations ensure broad protection across various age demographics.
- Widespread adoption of the vaccine is expected to significantly reduce varicella incidence.
Abstract:
Release of varicella vaccine is anticipated in early 1995. The vaccine has proved to be safe and effective in clinical trials over the past 12 years. Proposed recommendations for use include a single dose for routine vaccination of 12 to 18-month-old infants and for catch-up immunization of children from 18 months to 12 years of age and a two dose schedule to immunize susceptible adolescents and adults.