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In vivo evaluation of the Hydrolyser hydrodynamic thrombectomy catheter
V van Ommen1, F H van der Veen, M J Daemen
1Department of Cardiology, Academic Hospital Maastricht, University of Limburg, The Netherlands.
Purpose:
The authors evaluated a 7-F double-lumen thrombectomy catheter (Hydrolyser) in vivo.
Materials And Methods:
To evaluate efficacy, thrombectomy was performed 1, 4, or 8 days after local denudation in peripheral arteries (n = 18) and veins (n = 29) of nine goats. To evaluate safety, the reaction of the vessel wall to a functioning and nonfunctioning Hydrolyser catheter was evaluated in the peripheral arteries and veins of three goats 10 days after the procedure.
Results:
Reopening was achieved in all vessels with residual thrombus in 11% of arteries (two of 18) and 55% of veins (16 of 29). Slight intimal thickening was observed, but no difference was seen between the passage of a functioning versus nonfunctioning catheter.
Conclusions:
The Hydrolyser device can remove intravascular thrombus up to 8 days after induction. There was no difference in vessel wall reaction after the passage of a functioning and nonfunctioning catheter.