Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary cavitatory tuberculosis in children

D Vijayasekaran1, P Selvakumar, A Balachandran

  • 1Department of Pediatric Respiratory Diseases, Institute of Child Health, Egmore, Madras.

Indian Pediatrics
|September 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pace of Aging in older adults matters for healthspan and lifespan.

medRxiv : the preprint server for health sciences·2024
Same author

Utility of Transbronchial Cryobiopsy via Flexible Bronchoscope in Diagnosis of Isolated Pulmonary LCH: A Case Report.

Indian journal of pediatrics·2023
Same author

Etiology of Hemoptysis in Children and Adolescents - Multicentric Retrospective Data (2012-2021) From Chennai.

Indian pediatrics·2023
Same author

Recent advances in electrochemical sensor developments for detecting emerging pollutant in water environment.

Chemosphere·2022
Same author

TiO<sub>2</sub>/AgO composites by one step photo reduction technique as electron transport layers (ETL) for dye-sensitized solar cells.

Chemosphere·2022
Same author

Bronchial Dieulafoy Disease with Recurrent Life-threatening Hemoptysis.

Indian pediatrics·2021

Pediatric pulmonary cavitary tuberculosis is rare. Adding streptomycin to intensive anti-tuberculosis therapy improved treatment response in children with cavitary lung lesions.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Pulmonology

Background:

  • Pulmonary cavitary tuberculosis in children is uncommon and highly infectious.
  • Understanding pretreatment characteristics and treatment responses is crucial for managing this condition.

Purpose of the Study:

  • To analyze the pretreatment characteristics, clinical course, and treatment response to different anti-tuberculosis regimens in children with pulmonary cavitary lesions.
  • To evaluate the effectiveness of various treatment strategies in this pediatric population.

Main Methods:

  • Retrospective analysis of 27 children with cavitary pulmonary lesions treated at a TB Clinic.
  • Children received one of three anti-tuberculosis regimens including isoniazid, rifampicin, pyrazinamide, and streptomycin.
  • Follow-up and surveillance monitored treatment response and compliance in 23 children.

Related Experiment Videos

Main Results:

  • Thirty percent of affected children were under 3 years old with lower lobe involvement; older children had upper lobe involvement.
  • Eighty-five percent had a history of contact with an adult with tuberculosis; 70% tested positive for tuberculin.
  • Eleven of 23 children showed persistent radiological lesions after 9 months of therapy, though streptomycin inclusion improved outcomes.

Conclusions:

  • Pulmonary cavitary tuberculosis in children presents with specific demographic and radiological patterns.
  • While standard anti-tuberculosis drugs are used, incorporating streptomycin in the intensive phase may enhance treatment efficacy.
  • Further research is needed to optimize treatment protocols for pediatric pulmonary cavitary tuberculosis.