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Updated: Aug 2, 2026
09:46
Megakaryocyte Differentiation and Platelet Formation from Human Cord Blood-derived CD34+ Cells
Published on: December 27, 2017
Hemogram in normal newborn babies with special reference to platelet count
W Sasanakul1, S Singalavanija, P Hathirat
1Research Center, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand.
Summary
This study tracked newborn hemograms, finding that hemoglobin and hematocrit levels decrease after birth. White blood cell and platelet counts also change significantly in the first month of life.
Area of Science:
- Neonatal Medicine
- Hematology
- Pediatrics
Background:
- Establishing reference ranges for neonatal blood counts is crucial for accurate diagnosis.
- Normal hematological parameters in newborns undergo rapid changes in the first month of life.
Purpose of the Study:
- To establish reference ranges for complete blood counts in healthy newborns.
- To document the dynamic changes in hemoglobin, hematocrit, reticulocytes, white blood cells, and platelets during the first 30 days of life.
Main Methods:
- Prospective study of 318 healthy full-term newborns.
- Blood samples analyzed for hemoglobin, hematocrit, reticulocyte count, white blood cell count, and platelet count.
- Data collected from one hour to 30 days of age.
Main Results:
- Hemoglobin, hematocrit, and reticulocyte counts were highest in the first 72 hours and decreased thereafter.
- White blood cell counts were elevated at 12-24 hours and gradually decreased.
- Platelet counts peaked between 7-14 days and showed variation within the first 72 hours.
Conclusions:
- Neonatal hemogram values differ significantly from adult values and change rapidly in the first month.
- Platelet counts below 150 x 10(3)/microliters in newborns should be considered thrombocytopenia.
- These findings provide essential reference data for neonatal hematological assessment.
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