Related Experiment Videos
[Nausea and vomiting after gynecologic laparoscopies]
T Möllhoff1, G Burgard, T Prien
1Klinik und Poliklinik für Anästhesiologie und operative Intensivmedizin, Westfälische Wilhelms-Universität, Münster.
Summary
Postoperative nausea and vomiting (PONV) is more common in patients undergoing laparoscopy during the first 8 days of their menstrual cycle. Propofol anesthesia significantly reduces PONV and shivering compared to isoflurane.
Area of Science:
- Anesthesiology
- Gynecology
Background:
- Postoperative nausea and vomiting (PONV) is a common complication following anesthesia.
- The influence of the menstrual cycle on PONV incidence is not fully understood.
Purpose of the Study:
- To investigate the occurrence of PONV in relation to the menstrual cycle.
- To compare the incidence of PONV and postoperative shivering between isoflurane and propofol anesthesia.
Main Methods:
- 150 patients undergoing laparoscopy were randomly allocated to isoflurane or propofol anesthesia groups.
- All patients received droperidol as an antiemetic prophylaxis.
- Patients were ventilated with nitrous oxide/oxygen.
Main Results:
- PONV occurred in 29% of patients under isoflurane versus 5% under propofol (p < 0.05).
- PONV incidence was higher in patients undergoing procedures during the first 8 days of the menstrual cycle (29%, p < 0.05).
- Postoperative shivering was significantly more frequent with isoflurane (51%) than propofol (16%, p < 0.05).
Conclusions:
- The first 8 days of the menstrual cycle are associated with a significantly higher incidence of PONV.
- Propofol anesthesia leads to a significantly lower incidence of PONV and postoperative shivering compared to isoflurane.
- Propofol may also reduce postoperative pain incidence.