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Urethral stricture and semen quality

E D Yeboah1, J L Marmar

  • 1University of Ghana Medical School, Accra.

International Journal of Fertility and Menopausal Studies
|November 1, 1994
PubMed
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Early treatment for urethral stricture, particularly after infections, can improve male fertility. Testicular biopsies help diagnose ongoing infertility in affected men.

Area of Science:

  • Urology
  • Andrology
  • Reproductive Medicine

Background:

  • Urethral stricture is a known cause of male infertility.
  • The relationship between urethral stricture and fertility outcomes requires further investigation.

Purpose of the Study:

  • To investigate the impact of urethral stricture on male fertility.
  • To evaluate the effectiveness of treatment for urethral stricture in restoring fertility.

Main Methods:

  • Semen analysis was performed on fertile controls, infertile controls, and men with incomplete or complete urethral strictures.
  • Testicular biopsies were conducted on a subset of patients.
  • Etiology of strictures, primarily infectious urethritis, was identified.

Main Results:

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  • Surgical repair restored ejaculate in a significant portion of men with urethral strictures.
  • Normospermia was achieved in 22 men post-treatment.
  • Testicular biopsies indicated ductal obstruction in some cases and end-organ failure or other spermatogenic issues in others.

Conclusions:

  • Prompt medical treatment and surgical repair of urethral strictures can enhance male fertility, especially when caused by infectious urethritis.
  • Testicular biopsy is a valuable diagnostic tool for persistent infertility in men with urethral strictures.