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Metastatic carcinoid tumor in the brain
J Borowska-Lehman1, R Rzepko, L Chrostowski
1Department of Pathomorphology, School of Medicine, Gdańsk.
Folia Neuropathologica
|January 1, 1994
Summary
This case study details a rare metastatic carcinoid tumor in the brain, presenting as a stroke. Autopsy revealed primary tumors in the stomach and lung, highlighting unusual cellular polymorphism in the brain lesion.
Area of Science:
- Neuro-oncology
- Pathology
- Medical Imaging
Background:
- Carcinoid tumors are rare neuroendocrine neoplasms, with metastatic brain involvement being exceptionally uncommon.
- This case highlights the diagnostic and therapeutic challenges posed by metastatic carcinoid tumors presenting in the central nervous system.
Observation:
- A 52-year-old woman presented with stroke-like symptoms, revealing a hemorrhagic lesion in the cerebral hemisphere via CT scan.
- Histological examination confirmed a metastatic carcinoid tumor with massive hemorrhage.
- Subsequent CT scans identified a recurrent tumor near the surgical site, treated with palliative radiation therapy.
Findings:
- Autopsy revealed additional neoplastic tumors in the left lung and stomach, suggesting the stomach as a potential primary site.
- The irradiated brain tumor exhibited unusual cellular polymorphism, a notable finding in this metastatic carcinoid case.
Implications:
- This case underscores the importance of considering rare metastatic lesions in the differential diagnosis of brain tumors, especially in patients with a history of neuroendocrine tumors.
- The unusual cellular polymorphism warrants further investigation into the behavior and potential treatment strategies for metastatic carcinoid tumors.