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[Benefits and risks of topical steroids in childhood]
1Pädiatrische Pneumologie, Ostschweizerisches Kinderspital St. Gallen.
Insights
Inhaled glucocorticosteroids are key for childhood asthma but may cause systemic side effects. This review details risks, benefits, and best practices for using inhaled steroids safely in children.
Area of Science:
- Pediatric Pulmonology
- Pharmacology
- Endocrinology
Context:
- Inhaled glucocorticosteroids (IGCs) are primary anti-inflammatory agents for pediatric asthma.
- Concerns exist regarding potential systemic effects of IGCs, including growth, bone metabolism, and adrenal function.
Purpose:
- To review current literature on the clinical efficacy and safety of IGCs in children.
- To highlight potential side effects, optimal dosing, and inhalation techniques.
- To guide practitioners on appropriate indications and therapeutic strategies.
Summary:
- IGCs are effective for childhood asthma but require careful monitoring for systemic effects.
- Dose and inhalation technique significantly influence the risk-benefit profile.
- This review synthesizes data to support informed clinical decision-making.
Impact:
- Provides essential information for healthcare professionals managing pediatric asthma with IGCs.
- Facilitates evidence-based discussions on IGC safety with patients and families.
- Aims to optimize therapeutic outcomes while minimizing adverse events in children.
Abstract:
Inhaled glucocorticosteroids have become the cornerstone mode of anti-inflammatory treatment in children, especially with bronchial asthma. Many publications document the clinical efficacy of inhaled steroids and an increasing number of authors point out the possible systemic effects of topical steroids, such as effects on growth, impaired bone metabolism and adrenal suppression. The goal of this review article is to summarize published data. The author stresses possible relevant side effects in relation to dose and inhalation technique and focuses on the most appropriate indications and therapeutic modalities of inhaled steroids. The article yields valuable information for both practitioners and clinicians which will assist them in administering inhaled steroids and in discussing questions of safety with medical professionals and laymen.