[Ocular problems in children with homocystinuria]

Homocystinuria was diagnosed in 12 patients, aged 3-12 years. Myopia, ranged from -5.0 D to -20.0 D, and bilateral subluxation of lens were found in all children. In 8 eyes during follow-up luxation of lens was observed in 8 eyes, in 5 complicated by acute glaucoma. Surgical treatment, mostly pars plana lensectomia, was applied in 20 eyes. Normalisation of the intraocular pressure was achieved after surgery in 4 cases and improvement of visual acuity in 16 eyes. In 1 case of a boy after cerebral vessels infarct the intraocular pressure remained elevated and optic nerve atrophy developed. In 3 cases anterior scleral staphyloma was found.