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The trypanocidal effect of Cannabis sativa constituents in experimental animal trypanosomiasis
A J Nok1, S Ibrahim, S Arowosafe
1Department of Biochemistry, Ahmadu Bello University, Zaria-Nigeria.
Veterinary and Human Toxicology
|December 1, 1994
Abstract:
The effect of Cannabis sativa on trypanosome-infected rats was examined. An aqueous extract of the seeds administered at a dose of 50 mg/kg/d cured animals infected with Trypanosome brucei brucei of blood stream parasites. Six fractions eluted from the crude extract by column chromatography were assessed for trypanocidal properties. Of these, only 2 fractions retained trypanocidal activity by curing mice infected with T brucei brucei.