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Updated: Aug 9, 2026

3D Modeling of the Lateral Ventricles and Histological Characterization of Periventricular Tissue in Humans and Mouse
Published on: May 19, 2015
Right ventricular volume estimation with an ellipsoidal shell model and two-plane magnetic resonance imaging
S Denslow1, H B Wiles, L F McKellar
1South Carolina Children's Heart Center, Medical University of South Carolina, Charleston 29425-0680.
Abstract:
In patients with congenital and other heart disease, measurement of right ventricular (RV) volumes would be as useful as left ventricular (LV) volume measurement has been for diseases of the LV. Model-based techniques have had limited success. Simpson's rule (multislice) techniques require lengthy data collection and reduction. We investigated a technique for volume estimation with a new but simple geometric model. A retrospective patient study compared RV volumes from model-based calculations with dual-plane cine magnetic resonance (MR) imaging and multislice calculations with biplane cineangiography. Linear regression showed high correlation (r = 0.98, standard error of the estimate = 11.8 ml) between the two techniques, with a slope near unity. Comparison of calculated right and left stroke volumes also showed an excellent correlation (r = 0.93, standard error of the estimate = 10.4 ml) and a slope near unity. It is concluded that the ellipsoidal shell model can be used to estimate RV volume reliably and practically with dual-plane MR imaging.
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