Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Omeprazole overdose

R E Ferner1, T R Allison

  • 1West Midlands Poisons Unit, Dudley Road Hospital, Birmingham, UK.

Human & Experimental Toxicology
|November 1, 1993
PubMed
Summary
This summary is machine-generated.

Omeprazole overdose typically causes flushing, tachycardia, and headache. Pharmacokinetics of omeprazole remain unchanged even in overdose cases.

Related Experiment Videos

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond clinical toxicology: protecting our poisoned patients.

Journal of the Royal Society of Medicine·2026
Same author

Drug and therapeutics committees as guardians of safe and rational medicines use.

British journal of clinical pharmacology·2019
Same author

Crisis in the supply of medicines.

BMJ (Clinical research ed.)·2019
Same author

Adverse drug reactions in dermatology.

Clinical and experimental dermatology·2015
Same author

Systemic toxicity related to metal hip prostheses.

Clinical toxicology (Philadelphia, Pa.)·2014
Same author

Laughter and MIRTH (Methodical Investigation of Risibility, Therapeutic and Harmful): narrative synthesis.

BMJ (Clinical research ed.)·2013
Same journal

Establishment of a rat model of bronchopulmonary dysplasia complicated with pulmonary hypertension and its potential applications.

Human & experimental toxicology·2026
Same journal

Pulmonary iron oxide (Fe<sub>3</sub>O<sub>4</sub>) nanoparticle-biomolecule interactions modified during aging and metabolic syndrome disease progression.

Human & experimental toxicology·2026
Same journal

Retraction: Carvedilol alleviates the detrimental effects of azathioprine on hepatic tissues in experimental rats: Focusing on redox system, inflammatory and apoptosis pathways.

Human & experimental toxicology·2026
Same journal

Inhibition of store-operated calcium entry mitigates lipopolysaccharide-induced hepatotoxicity via modulating inflammatory and oxidative stress responses.

Human & experimental toxicology·2026
Same journal

Stevioside inhibits colorectal cancer progression by regulating macrophage polarization.

Human & experimental toxicology·2026
Same journal

Predictive factors of severe outcome in glufosinate ammonium poisoning: A retrospective study in Vietnam.

Human & experimental toxicology·2025
See all related articles

Area of Science:

  • Pharmacology
  • Clinical Toxicology

Background:

  • Limited data exists on omeprazole overdose clinical effects.
  • Understanding omeprazole pharmacokinetics in overdose is crucial for patient management.

Observation:

  • Two cases of omeprazole overdose were analyzed.
  • Key clinical manifestations included flushing, tachycardia, and headache.

Findings:

  • Omeprazole overdose clinical features are primarily flushing, tachycardia, and headache.
  • Pharmacokinetic parameters of omeprazole were not altered in overdose scenarios.

Implications:

  • This study provides initial insights into omeprazole overdose presentation.
  • Findings suggest that omeprazole metabolism is robust and not significantly affected by overdose, aiding in clinical decision-making.