Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Necrotizing vasculitis--relapse despite cytotoxic therapy

M Gordon1, R A Luqmani, D Adu

  • 1Renal Research Laboratory, Queen Elizabeth Hospital, Birmingham.

Advances in Experimental Medicine and Biology
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer's Disease mice.

Acta neuropathologica communications·2020
Same author

Multicenter Clinical Evaluation of the Revogene Strep A Molecular Assay for Detection of Streptococcus pyogenes from Throat Swab Specimens.

Journal of clinical microbiology·2020
Same author

Eastern Canadian Gastrointestinal Cancer Consensus Conference 2018.

Current oncology (Toronto, Ont.)·2019
Same author

Responding to the marauding terror attack: the police perspective.

BMJ military health·2018
Same author

Reply to: Who Should Bear the Cost of Convenience? A Cost-effectiveness Analysis Comparing External Beam and Brachytherapy Radiotherapy Techniques for Early Stage Breast Cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2017
Same author

[Topical therapy of the scalp].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2017
Same journal

Peptidomics in the Spotlight: Advanced Sample Treatment Techniques and Analytical Insights.

Advances in experimental medicine and biology·2026
Same journal

Methods for the Investigation of Protein-Ligands Interactions.

Advances in experimental medicine and biology·2026
Same journal

Sample Preparation Strategies for Microbial Cell Surface Proteomics: Integrating Shaving and Shotgun Approaches.

Advances in experimental medicine and biology·2026
Same journal

Proteomic Sample Preparation for the Petroleum Industry: A Biocorrosion Case Study.

Advances in experimental medicine and biology·2026
Same journal

Proteomic and Functional Comparison of Extracellular Vesicles from Wild-Type and Lyn-Deficient Stromal Cells.

Advances in experimental medicine and biology·2026
Same journal

Proteomic Analysis of Histone Sequence Variants and Post-translationally Modified Forms.

Advances in experimental medicine and biology·2026
See all related articles

Relapses are common in patients with vasculitis, with nearly one-third experiencing recurrence within months of diagnosis. Understanding these relapse patterns is crucial for effective patient management and treatment strategies.

Area of Science:

  • Rheumatology
  • Immunology
  • Internal Medicine

Background:

  • Vasculitis encompasses a group of rare diseases characterized by inflammation of blood vessels.
  • Recurrence of disease activity, or relapse, is a significant concern in managing vasculitis patients.
  • Predicting and understanding vasculitis relapse patterns is essential for optimizing long-term outcomes.

Purpose of the Study:

  • To describe the pattern and frequency of relapses in a cohort of patients diagnosed with vasculitis.
  • To identify factors that may influence the occurrence of vasculitis relapses.

Main Methods:

  • A consecutive series of 150 patients diagnosed with vasculitis were retrospectively analyzed.
  • Data on patient survival and disease relapse were collected and reviewed.

Related Experiment Videos

  • Relapse was defined as a recurrence of vasculitis activity.

    • Main Results:

    • Out of 150 patients, 124 survived for more than 3 months.
    • Relapse was observed in 42 of the 124 patients who survived beyond 3 months.
    • This indicates a notable rate of relapse in the studied vasculitis population.

    Conclusions:

    • Vasculitis relapses occur in a significant proportion of patients within the initial months of diagnosis.
    • Further research is needed to elucidate specific risk factors and develop targeted preventive strategies for vasculitis recurrence.