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Dopamine DA1 receptor activation reduces experimentally-induced gastritis in rats
1Department of Pharmacology and Therapeutics, Faculty of Medicine, University of Manitoba, Winnipeg, Canada.
General Pharmacology
|November 1, 1993
Abstract:
1. A selective dopamine DA1 receptor agonist, SKF38393, reduced the severity of experimentally-induced gastritis in rats. 2. This is the first such demonstration with a dopamine DA1 receptor agonist. 3. When considered together with other reported actions of D1/DA1 receptor agonists, these data confirm a significant gastroprotective role for dopamine.