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Two cases of long term dopamine D2 receptor blockade after depot neuroleptics
C Harasko-van der Meer1, T Brücke, S Wenger
1Neurological University Clinic, Vienna, Austria.
Journal of Neural Transmission. General Section
|January 1, 1993
Abstract:
Two patients with extrapyramidal side effects after the use of fluphenazine decanoate were evaluated by means of IBZM-SPECT. Dopamine D2 receptor occupancy 1.5 months after withdrawal still amounted to 83% and 50%. More attention should be focused on long term effects of neuroleptics.