Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

ISIS 5 possibilities

¹Royal Melbourne Hospital, Vic.

Australian and New Zealand Journal of Medicine

|December 1, 1993

Summary

This summary is machine-generated.

The ISIS 5 trial is evaluating five major therapeutic groups for heart attack treatment, including beta-blockers and thrombolytic drugs. Pilot studies will determine agent selection based on safety and efficacy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

First Constraint on Atmospheric Millicharged Particles with the LUX-ZEPLIN Experiment.

Physical review letters·2025

Same author

New Constraints on Cosmic Ray-Boosted Dark Matter from the LUX-ZEPLIN Experiment.

Physical review letters·2025

Same author

Dark Matter Search Results from 4.2 Tonne-Years of Exposure of the LUX-ZEPLIN (LZ) Experiment.

Physical review letters·2025

Same author

A new approach for assessing the radioecological risk associated with the legacy discharge of oil derived natural radioactivity in the UK North Sea.

Marine pollution bulletin·2025

Same author

Constraints on Covariant Dark-Matter-Nucleon Effective Field Theory Interactions from the First Science Run of the LUX-ZEPLIN Experiment.

Physical review letters·2024

Same author

Does it run in the family? - Improving radiological risk assessment in the coastal environment using taxonomic and phylogenetic perspectives in macroalgae species.

Marine pollution bulletin·2024

Same journal

Gastroenterological Society of Australia, Annual Scientific Meeting, May 1980.

Australian and New Zealand journal of medicine·2020

Same journal

'A touch of sugar'--a dangerous euphemism still alive and well.

Australian and New Zealand journal of medicine·2001

Same journal

Silent myocardial ischaemia following methysergide overdose.

Australian and New Zealand journal of medicine·2001

Same journal

Extensive jugular and upper limb thrombosis in a patient with factor V Leiden mutation and non-Hodgkin's lymphoma.

Australian and New Zealand journal of medicine·2001

Same journal

Visual loss as the presenting feature of giant cell arteritis.

Australian and New Zealand journal of medicine·2001

Same journal

Lymphoproliferative disease causing angioedema--an uncommon association.

Australian and New Zealand journal of medicine·2001

See all related articles

Area of Science:

Cardiology
Pharmacology

Background:

The ISIS 5 trial investigates novel therapeutic strategies for acute myocardial infarction.
Evaluating multiple drug classes is crucial for optimizing patient outcomes.

Purpose of the Study:

To assess the safety and efficacy of five distinct therapeutic groups in managing myocardial infarction.
To identify promising agents for further clinical investigation.

Main Methods:

The trial will evaluate intravenous beta-blocking agents.
Glucose-insulin-potassium (GIK) therapy will be assessed.
Newer anticoagulant/antithrombotic agents (hirudin, Hirulog), thrombolytics (r-PA), and surfactant agents (Rheothrx) are under consideration.

Main Results:

Related Experiment Videos

Pilot studies are currently underway to gather preliminary data.

Selection criteria prioritize scientific interest, safety, and efficacy.

Conclusions:

The ISIS 5 trial aims to advance cardiovascular medicine through rigorous evaluation of novel therapies.
Findings from pilot studies will guide the final selection of agents for comprehensive assessment.