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Potential pitfalls on the road to an effective HIV vaccine
1Dept of Immunology and Infectious Diseases, Johns Hopkins University School of Hygiene and PUblic Health, Baltimore, MD 21205.
Immunology Today
|February 1, 1994
Abstract:
Experimental vaccines for AIDS prophylaxis are being tested in larger and higher-risk populations. Here, David Schwartz, an advocate of HIV-vaccine research and development, highlights some of the concerns that have been voiced about this strategy and presents a simple mathematical model that considers the drawbacks to vaccine-induced expansion of HIV-specific CD4+ T cells.