[Clinical analysis of 150 cases with periampullary carcinoma]

This article reported 150 cases of patients with periampullary carcinoma, among which cancer of 85 cases was in the head of pancreas, 26 in lower part of the common bile-duct, and 21 in ampulla of Vater and 18 in duodenal papilla. In 150 patients, pancreatoduodenectomy was performed in 53 cases but one had total pancreatectomy with a total resection rate of 36%. Resectability was high with cancer in ampulla and duodenal papilla, with a resection rate of 89.5% and 83.3%, respectively. The lowest resection rate, 14.1%, was in patients with cancer in head of the pancreas. Twenty cases had postoperative complications, the morbidity rate was 13.3%. Postoperative death occurred in 9 cases with a mortality rate of 6%. The resection group and non-resection group had 7.5 percent and 5.2 percent of the mortality respectively. Following-up showed that the 3 year and 5 year survival rates were 31.8% and 11.8% respectively. Fifty-four cases with resections had a mean survival period of 16.7 months. Ampullary carcinoma group had the longest survival period, 22.4 months, but non-resection group, all had bile-intestinal shunt, only 4.8 months.