Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sympathetic nervous system: aging and exercise

N T Scarpace1, D T Lowenthal

  • 1GRECC, Department of Veterans Affairs Medical Center, Gainesville, FL 32608-1197.

Southern Medical Journal
|May 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Endoscopic evaluation of the effects of indobufen and aspirin in healthy volunteers.

American journal of therapeutics·2004
Same author

An uncommon cause of unsteady gait in an elderly gentleman.

International urology and nephrology·2002
Same author

Clinical pharmacology-physiology conference. A chrono-therapeutic approach to the treatment of hypertension.

International urology and nephrology·2002
Same author

Effects of fosinopril or sustained-release verapamil on blood pressure and serum catecholamine concentrations in elderly hypertensive men.

American journal of therapeutics·2001
Same author

Survival of vascular access during daily and three times a week hemodialysis.

Clinical nephrology·2001
Same author

Androgens, anabolic-androgenic steroids, and inhibitors.

American journal of therapeutics·2001
Same journal

The Five Essential Concepts of Developmental Medicine: A Medical Paradigm for People with Developmental Disabilities.

Southern medical journal·2026
Same journal

α-Gal Syndrome in the South: Why We Need Treatment Trials, Not Just Tick Prevention.

Southern medical journal·2026
Same journal

Association between Main Pancreatic Duct Size, Comorbidities, and Fistula Formation after Whipple Procedure for Pancreatic Cancer.

Southern medical journal·2026
Same journal

Impact of Temperature Variation on Patients with Acute Severe Asthma.

Southern medical journal·2026
Same journal

Assessing the Accuracy and Reliability of ChatGPT-4 to Answer Clinical EHR Messages in Sports Medicine.

Southern medical journal·2026
Same journal

Diagnostic Utility and Clinical Implications of Inpatient Fecal Occult Blood Testing.

Southern medical journal·2026
See all related articles

Aging alters catecholamine regulation, potentially increasing hypertension risk. Exercise training, however, lowers blood pressure in hypertensive individuals by reducing catecholamine synthesis.

Area of Science:

  • Cardiovascular Physiology
  • Neuroendocrinology
  • Aging Research

Background:

  • Aging is linked to elevated catecholamines and increased sympathetic nervous system activity.
  • These age-related changes may contribute to the higher prevalence of hypertension in older adults.
  • The catecholaminergic system's adaptability is compromised with age, affecting responses to environmental challenges.

Purpose of the Study:

  • To investigate the relationship between aging, catecholamine regulation, and hypertension.
  • To explore the impact of exercise training on blood pressure and catecholamine levels in hypertensive individuals.

Main Methods:

  • The study examines alterations in catecholamine regulation associated with aging.
  • It analyzes the effects of exercise training on blood pressure in both young and elderly hypertensive subjects.

Related Experiment Videos

Main Results:

  • Aging is associated with elevated resting and stress-induced catecholamines, suggesting increased sympathetic activity.
  • Exercise training effectively reduces systolic and diastolic blood pressure in hypertensive individuals across age groups.
  • A potential mechanism for exercise's benefit is the observed reduction in catecholamine synthesis post-training.

Conclusions:

  • Age-related changes in catecholamine regulation may predispose individuals to hypertension.
  • Exercise training offers a beneficial intervention for hypertension, potentially through modulation of the catecholaminergic system.
  • Targeting catecholamine synthesis through exercise could be a key strategy for managing hypertension in aging populations.