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Bilateral acetylsulfapyridine nephrolithiasis associated with chronic sulfasalazine therapy
E Erturk1, J B Casemento, K R Guertin
1Department of Urology, University of Rochester, New York 14642.
The Journal of Urology
|June 1, 1994
Abstract:
We report on formation of bilateral renal calculi secondary to sulfasalazine therapy for juvenile rheumatoid arthritis. The condition was successfully treated with extracorporeal shock wave lithotripsy. Analysis of the fragments with thin layer chromatography and nuclear magnetic resonance revealed acetylsulfapyridine, a metabolite of sulfasalazine.