Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Graft adherence to de-epithelialized surfaces: a comparative study

M J Tavis, J W Thornton, J H Harney

    Annals of Surgery
    |November 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The Mineralocorticoid Receptor-How to Get Away with Promiscuity: Evolution of Hormone-Receptor Complexity by Molecular Exploitation. Science 312: 97-101, 2006.

    Journal of the American Society of Nephrology : JASN·2023
    Same author

    [A critical carol : Being an essay on anemia, suffocation, starvation, and other forms of intensive care, after the manner of Dickens].

    Der Anaesthesist·2020
    Same author

    Enhancing analytical accuracy of intravascular electrochemical oxygen sensors via nitric oxide release using S-nitroso-N-acetyl-penicillamine (SNAP) impregnated catheter tubing.

    Talanta·2019
    Same author

    Rodent Skeletal Muscle Metabolomic Changes Associated With Static Cold Storage.

    Transplantation proceedings·2019
    Same author

    [The old man and the I sea U : Essay on faith, fate and evidence - after the manner of Hemingway].

    Der Anaesthesist·2016
    Same author

    [Alice in intensiveland : Essay on nonsense and common sense in intensive care unit after the manner of Lewis Carroll].

    Der Anaesthesist·2013
    Same journal

    Real-world Safety and Performance of the Symani Surgical System® in Microsurgical Reconstructive Procedures: Primary Results from the PRIMO Study.

    Annals of surgery·2026
    Same journal

    Revisiting Simultaneous Liver and Kidney Transplantation from Donors After Circulatory Death in the Era of Machine Perfusion Technologies: A US Nationwide Analysis of 10,687 Cases.

    Annals of surgery·2026
    Same journal

    The International Medical Graduate Paradox.

    Annals of surgery·2026
    Same journal

    Defining the Incremental Value of Endoscopic Ultrasound in Assessing Pancreatic Cystic Neoplasms.

    Annals of surgery·2026
    Same journal

    Trends in Metabolic and Bariatric Surgery and GLP-1 Receptor Agonist Use Among Adolescents with Severe Obesity.

    Annals of surgery·2026
    Same journal

    The Ambulatory Surgery Center Paradox: Why 60% of Surgeries Occur Where 2% of AI Research Happens.

    Annals of surgery·2026
    See all related articles

    Modified collagen membranes show superior graft adherence in early wound healing phases. Biologically derived materials are promising for synthetic wound dressings over inert options.

    Area of Science:

    • Biomaterials Science
    • Wound Healing Research
    • Tissue Engineering

    Background:

    • Graft adherence is crucial for successful tissue regeneration.
    • Early graft adherence involves a fibrin-dependent phase (Phase I) and later fibrovascular ingrowth (Phase II).

    Purpose of the Study:

    • To evaluate early graft adherence of various materials during the fibrin-dependent phase.
    • To compare adherence on different tissue surfaces (dermal, fascial, granulating).

    Main Methods:

    • Assessed adherence of autograft, homograft, heterograft, silicone membrane, and modified collagen membrane.
    • Tested adherence at 5 and 72 hours on rat dermal, fascial, and granulating surfaces.
    • Focused on the fibrin-dependent Phase I adherence.

    Related Experiment Videos

    Main Results:

    • Modified collagen membrane exhibited superior adherence on dermal and fascial surfaces at both time points.
    • Autografts and homografts showed significantly higher adherence on granulating surfaces at 72 hours.
    • Inert silicone membrane consistently demonstrated the lowest adherence.

    Conclusions:

    • Biologically derived materials, like collagen, are more promising for synthetic wound dressings than inert materials.
    • Fibrin plays a key role in Phase I graft adherence.
    • Collagen appears to be primarily responsible for early graft adherence.