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Updated: Aug 8, 2026

Biosensor for Detection of Antibiotic Resistant Staphylococcus Bacteria
Published on: May 8, 2013
Bacteriological studies of contamination of hydrophilic contact lenses with Staphylococcus epidermitis
Abstract:
An attempt was made to contaminate hydrophilic contact lens material with Staphylococcus epidermitis. This study was initiated as a result of some clinical investigations which had revealed the presence of coagulase-negative staphylococcal infection in eyes fitted with this type of contact lens. It was though particularly relevant in view of the known association of some strains of this organism with other plastic prostheses. In vitro cultures proved unsuccessful in demonstrating the ability of this bacterium to metabolize the lens material.
Insights
Hydrophilic contact lens material could not be contaminated by Staphylococcus epidermidis in vitro. This study investigated the link between this bacterium and contact lens infections, finding no evidence of material metabolism.
Area of Science:
- Ophthalmology
- Microbiology
- Biomaterials Science
Background:
- Clinical investigations noted coagulase-negative staphylococcal infections in patients using hydrophilic contact lenses.
- Staphylococcus epidermidis is known to associate with other plastic prostheses, prompting further research.
- The study aimed to assess the potential for bacterial contamination and metabolism of contact lens materials.
Observation:
- An attempt was made to contaminate hydrophilic contact lens material with Staphylococcus epidermidis.
- In vitro cultures were utilized to observe bacterial interaction with the lens material.
Findings:
- In vitro cultures were unsuccessful in demonstrating that Staphylococcus epidermidis can metabolize hydrophilic contact lens material.
- The study did not establish a direct metabolic interaction between the bacterium and the lens material under the tested conditions.
Implications:
- Further research is needed to understand the mechanisms behind Staphylococcus epidermidis infections associated with hydrophilic contact lenses.
- Findings suggest that the lens material itself may not be a direct nutrient source for the bacteria.
- This research contributes to understanding biomaterial-associated infections in ophthalmology.
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