Immunological findings of serological tests in steroid-responsive sensorineural hearing loss

The following results were obtained after serological examination of 11 patients with steroid-responsive SNHL including a case with the aortitis syndrome (Takayasu disease) and sensorineural hearing loss, and 3 cases with positive syphilitic reaction. i) Abnormalities of serum immunoglobulins IgG or IgM level were found in 6 of 11 cases (54.5%), ii) Abnormalities in lymphocyte subsets were found in 7 of 14 cases (50.0%), iii) Immunologic abnormalities were thought to be present in patients with steroid-responsive SNHL and related diseases, but no findings specific to either group were observed.