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Dystrophin-related protein in Becker muscular dystrophy
I Higuchi1, T Niiyama, H Fukunaga
1Third Department of Internal Medicine, Faculty of Medicine, Kagoshima University.
Internal Medicine (Tokyo, Japan)
|June 1, 1994
Abstract:
A benign Becker muscular dystrophy (BMD) patient with a marked decrease in dystrophin exhibited remarkable expression of dystrophin-related protein (DRP) on most of the muscle cell membrane. A phenotypic Duchenne muscular dystrophy patient with a truncated form of dystrophin exhibited no DRP expression on the muscle cell membrane except for the neuromuscular junction. Increased DRP expression might compensate for a lack of dystrophin in some BMD patients.