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Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers
Published on: March 6, 2009
[Evaluation of immunoreactivity of class 2 HLA-determinant using mixed lymphocyte culture]
Klinicheskaia Laboratornaia Diagnostika
|January 1, 1994
Abstract:
Immunoreactivity (proliferative capacity) of normal donor peripheral blood mononuclears expressing HLA-DR antigens in MLC test was studied. HLA-DR cellular phenotype was found to influence the intensity of proliferative response. HLA-DR highly reactive (HLA-DR5, HLA-DR7, HLA-DR4) and low-reactive (HLA-DR1, HLA-DR2, HLA-DR6) determinants were distinguished.

