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Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
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Injury and development in polycystic kidney disease

J P Calvet1

  • 1Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City 66160-7421.

Current Opinion in Nephrology and Hypertension
|May 1, 1994
PubMed
Summary

Polycystic kidney disease (PKD) cyst formation may stem from a common mechanism: arrested development. This theory suggests immature epithelial cells lock in a unique state, potentially due to subcritical injury-induced dedifferentiation.

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