[Erythrocyte membrane during shock stage in burned rats]

The anion transport property is the one of the most important functions of the erythrocyte. In this paper a new method is used to measure the NO2- and Cl- ions transport across the erythrocyte membrane in burned rats. It was found that the NO2- and Cl- transport rate across erythrocyte membrane became slower during shock stage in burned rats, being contrary to the results found in heat-treated erythrocytes in vitro. By using a specific inhibitor of anion transport, DIDS, it was shown that the abnormality of NO2- transport across the erythrocyte membrane in burned rats is due probably to a damage of extracellular domain of band 3 protein. The authors consider that the influence of membranotoxic factors and the disturbance of energy metabolism during burn shock stage are accounted for all the noticed alterations.