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Peripheral ulcerative keratitis and malignancies

M Sainz de la Maza1, C S Foster

  • 1Ocular Immunology Service, Massachusetts, Eye and Ear Infirmary, Boston 02114.

Cornea
|July 1, 1994
PubMed
Summary
This summary is machine-generated.

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Peripheral ulcerative keratitis (PUK) can signal underlying cancers. Meticulous diagnosis is crucial, as PUK may indicate malignancies like leukemia or eyelid carcinoma.

Area of Science:

  • Ophthalmology
  • Oncology

Background:

  • Peripheral ulcerative keratitis (PUK) is typically associated with autoimmune diseases.
  • Unusual etiologies for PUK, including malignancies, must be considered in diagnosis.

Observation:

  • Two patients presented with PUK.
  • Diagnostic evaluation revealed underlying malignancies in both cases.

Findings:

  • One patient was diagnosed with chronic myelogenous leukemia.
  • The other patient was diagnosed with a sebaceous cell carcinoma of the eyelid.

Implications:

  • These cases highlight the importance of considering malignancy in the differential diagnosis of PUK.
  • Thorough diagnostic investigation is essential for identifying rare but serious causes of PUK.

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