Related Experiment Videos
Phosphorylative inactivation of rifampicin by Nocardia otitidiscaviarum
1Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.
The Journal of Antimicrobial Chemotherapy
|June 1, 1994
Abstract:
Rifampicin was inactivated by Nocardia otitidiscaviarum to yield two products designated RIP-3 and RIP-4. The full structures of RIP-3 and RIP-4 were determined to be 21-(O-phosphoryl) rifampicin and 3-formyl-21-(O-phosphoryl) rifamycin SV, respectively, but neither product had any antimicrobial activity.