Related Experiment Video
Updated: Jul 28, 2026
10:14
Using Adeno-associated Virus as a Tool to Study Retinal Barriers in Disease
Published on: April 19, 2015
Adverse reactions during retinal fluorescein angiography
1Vitreo-Retinal Foundation, Memphis, TN 38120.
Journal of the American Optometric Association
|July 1, 1994
Summary
Fast sequence retinal fluorescein angiography is a safe diagnostic test, with nausea and urticaria being the most common adverse reactions. While serious anaphylaxis is rare, preparedness for such events is advised.
Area of Science:
- Ophthalmology
- Optometry
- Diagnostic Imaging
Background:
- Fast sequence retinal fluorescein angiography is a common optometric diagnostic tool.
- The procedure generally has a low incidence of serious adverse reactions.
- This study aimed to document adverse reactions in a large patient cohort.
Purpose of the Study:
- To determine the incidence of adverse reactions associated with fast sequence retinal fluorescein angiography.
- To evaluate the safety profile of this diagnostic procedure in an optometric setting.
Main Methods:
- Retrospective review of 1,173 patient charts.
- Patients received intravenous sodium fluorescein (500 mg).
- Adverse reactions were recorded from patient charts.
Main Results:
- Nausea (0.8%) and urticaria (0.6%) were the most frequent adverse events.
- Other reported reactions included emesis and hypoglycemia.
- Dye extravasation occurred in 0.2% of patients; no acute anaphylaxis was observed.
Conclusions:
- Fast sequence retinal fluorescein angiography is a relatively safe diagnostic procedure.
- Clinicians should maintain preparedness for potential acute anaphylaxis, despite its rarity.
- The study highlights the importance of safety protocols in diagnostic angiography.
Related Concept Videos
01:28Imaging Studies for Cardiovascular System V: CT
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
01:27Imaging Studies III: Computed Tomography
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
01:19Imaging Studies VII: Vascular Imaging
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
01:27Diabetic Retinopathy
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...