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[Acute segmental hemorrhagic penicillin-associated colitis in a 32-year-old patient]
C Benz1, B Kohler, J F Riemann
1Medizinische Klinik C des Klinikums der Stadt Ludwigshafen/Rhein.
Abstract:
We report on a 32-year old patient who developed acute abdominal cramps and bloody diarrhea two days after taking phenoxymethyl penicillin. After excluding other causes, we diagnosed an acute segmental hemorrhagic penicillin associated colitis. In this case report we discuss the literature on this diagnosis and present the etiology, course, prognosis, and differential diagnosis of this entity.
Insights
A patient developed severe gastrointestinal issues, including bloody diarrhea, after taking phenoxymethyl penicillin. This case highlights penicillin-associated colitis as a potential diagnosis for such symptoms.
Area of Science:
- Gastroenterology
- Pharmacology
Background:
- Antibiotic-associated colitis is a known complication of various antimicrobial agents.
- Phenoxymethyl penicillin, a widely used antibiotic, has been rarely associated with colitis.
Observation:
- A 32-year-old patient presented with acute abdominal cramps and bloody diarrhea.
- Symptoms began two days after initiating phenoxymethyl penicillin therapy.
Findings:
- Diagnosis of acute segmental hemorrhagic penicillin-associated colitis was established after excluding other causes.
- The case underscores a rare but significant adverse drug reaction to phenoxymethyl penicillin.
Implications:
- Clinicians should consider penicillin-associated colitis in patients with compatible symptoms post-antibiotic use.
- Early recognition and discontinuation of the offending agent are crucial for favorable prognosis.